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The critical role of toll-like receptors - From microbial recognition to autoimmunity: A comprehensive review

Toll-like receptors (TLRs) constitute an important mechanism in the activation of innate immune cells including monocytes, macrophages and dendritic cells. Macrophage activation by TLRs is pivotal in the initiation of the rapid expression of pro-inflammatory cytokines TNF, IL-1β and IL-6 whilst prom...

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Publicat a:Autoimmun Rev
Autors principals: Jiménez-Dalmaroni, Maximiliano Javier, Gerswhin, M. Eric, Adamopoulos, Iannis E.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679489/
https://ncbi.nlm.nih.gov/pubmed/26299984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autrev.2015.08.009
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