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Targeted Delivery of Gold Nanoparticle Contrast Agents for Reporting Gene Detection by Magnetic Resonance Imaging()

Detection of protein expression by MRI requires a high payload of Gd(III) per protein binding event. Presented here is a targeted AuDNA nanoparticle capable of delivering several hundred Gd(III) chelates to the HaloTag reporter protein. Incubating this particle with HaloTag-expressing cells produced...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Vistain, Luke F., Rotz, Matthew W., Rathore, Richa, Preslar, Adam T., Meade, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679476/
https://ncbi.nlm.nih.gov/pubmed/26505558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc06565h
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