Altered Escherichia coli membrane protein assembly machinery allows proper membrane assembly of eukaryotic protein vitamin K epoxide reductase

Functional overexpression of polytopic membrane proteins, particularly when in a foreign host, is often a challenging task. Factors that negatively affect such processes are poorly understood. Using the mammalian membrane protein vitamin K epoxide reductase (VKORc1) as a reporter, we describe a gene...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hatahet, Feras, Blazyk, Jessica L., Martineau, Eugenie, Mandela, Eric, Zhao, Yongxin, Campbell, Robert E., Beckwith, Jonathan, Boyd, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679017/
https://ncbi.nlm.nih.gov/pubmed/26598701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521260112
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