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Altered Escherichia coli membrane protein assembly machinery allows proper membrane assembly of eukaryotic protein vitamin K epoxide reductase
Functional overexpression of polytopic membrane proteins, particularly when in a foreign host, is often a challenging task. Factors that negatively affect such processes are poorly understood. Using the mammalian membrane protein vitamin K epoxide reductase (VKORc1) as a reporter, we describe a gene...
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Vydáno v: | Proc Natl Acad Sci U S A |
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Hlavní autoři: | , , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
National Academy of Sciences
2015
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4679017/ https://ncbi.nlm.nih.gov/pubmed/26598701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521260112 |
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