Cartilage boundary lubrication synergism is mediated by hyaluronan concentration and PRG4 concentration and structure

BACKGROUND: Proteoglycan 4 (PRG4) and hyaluronan (HA) are key synovial fluid constituents that contribute synergistically to cartilage boundary lubrication; however, the effects of their concentrations as well as their structure, both of which can be altered in osteoarthritis, on this functional syn...

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Bibliographic Details
Published in:BMC Musculoskelet Disord
Main Authors: Ludwig, Taryn E., Hunter, Miles M., Schmidt, Tannin A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678696/
https://ncbi.nlm.nih.gov/pubmed/26666513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-015-0842-5
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