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Quantitative proteomics signature profiling based on network contextualization

BACKGROUND: We present a network-based method, namely quantitative proteomic signature profiling (qPSP) that improves the biological content of proteomic data by converting protein expressions into hit-rates in protein complexes. RESULTS: We demonstrate, using two clinical proteomics datasets, that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Direct
Hauptverfasser: Goh, Wilson Wen Bin, Guo, Tiannan, Aebersold, Ruedi, Wong, Limsoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678536/
https://ncbi.nlm.nih.gov/pubmed/26666224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0098-x
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