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Distinct promoter activation mechanisms modulate noise-driven HIV gene expression

Latent human immunodeficiency virus (HIV) infections occur when the virus occupies a transcriptionally silent but reversible state, presenting a major obstacle to cure. There is experimental evidence that random fluctuations in gene expression, when coupled to the strong positive feedback encoded by...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Chavali, Arvind K., Wong, Victor C., Miller-Jensen, Kathryn
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678399/
https://ncbi.nlm.nih.gov/pubmed/26666681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17661
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