Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors

Tertiary lymphoid organs (TLOs) emerge during nonresolving peripheral inflammation, but their impact on disease progression remains unknown. We have found in aged Apoe(−/−) mice that artery TLOs (ATLOs) controlled highly territorialized aorta T cell responses. ATLOs promoted T cell recruitment, prim...

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Publié dans:Immunity
Auteurs principaux: Hu, Desheng, Mohanta, Sarajo K., Yin, Changjun, Peng, Li, Ma, Zhe, Srikakulapu, Prasad, Grassia, Gianluca, MacRitchie, Neil, Dever, Gary, Gordon, Peter, Burton, Francis L., Ialenti, Armando, Sabir, Suleman R., McInnes, Iain B., Brewer, James M., Garside, Paul, Weber, Christian, Lehmann, Thomas, Teupser, Daniel, Habenicht, Livia, Beer, Michael, Grabner, Rolf, Maffia, Pasquale, Weih, Falk, Habenicht, Andreas J.R.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678289/
https://ncbi.nlm.nih.gov/pubmed/26084025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.05.015
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