Pre-stimulation of CD81 expression by resting B cells increases proliferation following EBV infection, but the overexpression of CD81 induces the apoptosis of EBV-transformed B cells

Hepatitis C virus (HCV) E2 protein binds to CD81, which is a component of the B cell co-stimulatory complex. The E2-CD81 interaction leads to B cell proliferation, protein tyrosine phosphorylation and to the hypermutation of immunoglobulin genes. Epidemiological studies have reported a high prevalen...

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Bibliografiska uppgifter
I publikationen:Int J Mol Med
Huvudupphovsmän: PARK, GA BIN, KIM, DAEJIN, PARK, SUNG JAE, LEE, HYUN-KYUNG, KIM, JI HYUN, KIM, YEONG SEOK, PARK, SAE-GWANG, CHOI, IN-HAK, YOON, SUNG HO, LEE, YOUN JAE, PAENG, SUNGHWA, HUR, DAE YOUNG
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2015
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678167/
https://ncbi.nlm.nih.gov/pubmed/26498453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2372
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