Anomalous Dynamics of a Lipid Recognition Protein on a Membrane Surface

Pleckstrin homology (PH) domains are lipid-binding modules present in peripheral membrane proteins which interact with phosphatidyl-inositol phosphates (PIPs) in cell membranes. We use multiscale molecular dynamics simulations to characterize the localization and anomalous dynamics of the DAPP1 PH d...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Yamamoto, Eiji, Kalli, Antreas C., Akimoto, Takuma, Yasuoka, Kenji, Sansom, Mark S. P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677404/
https://ncbi.nlm.nih.gov/pubmed/26657413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18245
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