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Delineation of two functional regions of transcription factor TFIIB.

Human transcription factor TFIIB, a protein of 316 amino acids, was subjected to limited proteolysis in order to define stable structural domains. We find that the C-terminal region of TFIIB, residues 106-316, is relatively stable, while the N-terminal region is very sensitive to proteases. Like ful...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Barberis, A, Müller, C W, Harrison, S C, Ptashne, M
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1993
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8516311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.12.5628
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