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Epigenomic Reprogramming of Adult Cardiomyocyte-Derived Cardiac Progenitor Cells

It has been believed that mammalian adult cardiomyocytes (ACMs) are terminally-differentiated and are unable to proliferate. Recently, using a bi-transgenic ACM fate mapping mouse model and an in vitro culture system, we demonstrated that adult mouse cardiomyocytes were able to dedifferentiate into...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Yiqiang, Zhong, Jiang F, Qiu, Hongyu, Robb MacLellan, W., Marbán, Eduardo, Wang, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677315/
https://ncbi.nlm.nih.gov/pubmed/26657817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17686
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