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The interplay of the Notch signaling in hepatic stellate cells and macrophages determines the fate of liver fibrogenesis

Hepatic stellate cells (HSCs) known as “master producers” and macrophages as “master regulators”, are the key cell types that strongly contribute to the progression of liver fibrosis. Since Notch signaling regulates multiple cellular processes, we aimed to study the role of Notch signaling in HSCs d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bansal, Ruchi, van Baarlen, Joop, Storm, Gert, Prakash, Jai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677309/
https://ncbi.nlm.nih.gov/pubmed/26658360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18272
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