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The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance
The transcription factor, nuclear factor erythroid 2 p45-related factor 2 (Nrf2), acts as a sensor of oxidative or electrophilic stresses and plays a pivotal role in redox homeostasis. Oxidative or electrophilic agents cause a conformational change in the Nrf2 inhibitory protein Keap1 inducing the n...
Gardado en:
| Publicado en: | Oxid Med Cell Longev |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Hindawi Publishing Corporation
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4677237/ https://ncbi.nlm.nih.gov/pubmed/26697129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1958174 |
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