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Molecular mechanisms of antigen retrieval: antigen retrieval reverses steric interference caused by formalin-induced crosslinks

The overwhelming majority of antibodies useful for formalin fixed, paraffin embedded (FFPE) tissues require antigen retrieval to reverse the effect of formalin fixation and re-establish immunoreactivity. How this reversal happens is poorly understood. We developed a new experimental model for studyi...

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Bibliographic Details
Published in:Biotech Histochem
Main Authors: Bogen, SA, Vani, K, Sompuram, SR
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676902/
https://ncbi.nlm.nih.gov/pubmed/19886757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10520290903039078
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