A Case Study Comparing Quantitative Stability/Flexibility Relationships Across Five Metallo-β-Lactamases highlighting differences within NDM-1

The Distance Constraint Model (DCM) is an ensemble-based biophysical model that integrates thermodynamic and mechanical viewpoints of protein structure. The DCM outputs a large number of structural characterizations that collectively allow for Quantified Stability/Flexibility Relationships (QSFR) to...

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Библиографические подробности
Опубликовано в: :Methods Mol Biol
Главные авторы: Brown, Matthew C., Verma, Deeptak, Russell, Christian, Jacobs, Donald J., Livesay, Dennis R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676803/
https://ncbi.nlm.nih.gov/pubmed/24061924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-658-0_12
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