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Role of B cell receptor signaling in IL-10 production by normal and malignant B-1 cells

B-1 cells are considered innate immune cells that produce the majority of natural antibodies. B-1 cell responses to B cell receptor (BCR) and Toll-like receptor (TLR) ligation are tightly regulated owing to the cross-reactivity to self-antigens. CD5 has been shown to play a major role in down regula...

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Détails bibliographiques
Publié dans:Ann N Y Acad Sci
Auteurs principaux: Alhakeem, Sara S., Sindhava, Vishal J., McKenna, Mary K., Gachuki, Beth W., Byrd, John C., Muthusamy, Natarajan, Bondada, Subbarao
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676736/
https://ncbi.nlm.nih.gov/pubmed/26096907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12802
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