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Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants
Therapeutic performance of recombinant antibodies relies on two independent mechanisms: antigen recognition and Fc-mediated antibody effector functions. Interaction of Fc-fragment with different FcR triggers antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity and determine...
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| Publicado en: | PLoS One |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4676693/ https://ncbi.nlm.nih.gov/pubmed/26657484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143520 |
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