Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants

Therapeutic performance of recombinant antibodies relies on two independent mechanisms: antigen recognition and Fc-mediated antibody effector functions. Interaction of Fc-fragment with different FcR triggers antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity and determine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Dashivets, Tetyana, Thomann, Marco, Rueger, Petra, Knaupp, Alexander, Buchner, Johannes, Schlothauer, Tilman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676693/
https://ncbi.nlm.nih.gov/pubmed/26657484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143520
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg