Time-Dependent Progression of Demyelination and Axonal Pathology in MP4-Induced Experimental Autoimmune Encephalomyelitis

BACKGROUND: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by inflammation, demyelination and axonal pathology. Myelin basic protein/proteolipid protein (MBP-PLP) fusion protein MP4 is capable of inducing chronic experimental autoimmune encephalomy...

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Опубликовано в: :PLoS One
Главные авторы: Prinz, Johanna, Karacivi, Aylin, Stormanns, Eva R., Recks, Mascha S., Kuerten, Stefanie
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676607/
https://ncbi.nlm.nih.gov/pubmed/26658811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144847
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