Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain

Balamuthia mandrillaris , a free-living ameba, causes rare but frequently fatal granulomatous amebic encephalitis (GAE). Few patients have survived after receiving experimental drug combinations, with or without brain lesion excisions. Some GAE survivors have been treated with a multi-drug regimen i...

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Pubblicato in:Parasitol Res
Autori principali: Roy, Sharon L., Atkins, Jane T., Gennuso, Rosemaria, Kofos, Danny, Sriram, Rama R., Dorlo, Thomas P.C., Hayes, Teresa, Qvarnstrom, Yvonne, Kucerova, Zuzana, Guglielmo, B. Joseph, Visvesvara, Govinda S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676568/
https://ncbi.nlm.nih.gov/pubmed/26329128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00436-015-4684-8
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