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Escape from Mitotic Arrest: An Unexpected Connection Between Microtubule Dynamics and Epigenetic Regulation of Centromeric Chromatin in Schizosaccharomyces pombe

Accurate chromosome segregation is necessary to ensure genomic integrity. Segregation depends on the proper functioning of the centromere, kinetochore, and mitotic spindle microtubules and is monitored by the spindle assembly checkpoint (SAC). In the fission yeast Schizosaccharomyces pombe, defects...

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Foilsithe in:Genetics
Main Authors: George, Anuja A., Walworth, Nancy C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2015
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676536/
https://ncbi.nlm.nih.gov/pubmed/26510788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.181792
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