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Regulation of CTP Synthase Filament Formation During DNA Endoreplication in Drosophila

CTP synthase (CTPsyn) plays an essential role in DNA, RNA, and lipid synthesis. Recent studies in bacteria, yeast, and Drosophila all reveal a polymeric CTPsyn structure, which dynamically regulates its enzymatic activity. However, the molecular mechanism underlying the formation of CTPsyn polymers...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Wang, Pei-Yu, Lin, Wei-Cheng, Tsai, Yi-Cheng, Cheng, Mei-Ling, Lin, Yu-Hung, Tseng, Shu-Heng, Chakraborty, Archan, Pai, Li-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676535/
https://ncbi.nlm.nih.gov/pubmed/26482795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.180737
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