Evidence that a neutrophil–keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis

The response of psoriasis to antibodies targeting the interleukin (IL)-23/IL-17A pathway suggests a prominent role of T-helper type-17 (Th17) cells in this disease. We examined the clinical and immunological response patterns of 100 subjects with moderate-to-severe psoriasis receiving 3 different in...

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Detalhes bibliográficos
Publicado no:Exp Dermatol
Main Authors: Reich, Kristian, Papp, Kim A, Matheson, Robert T, Tu, John H, Bissonnette, Robert, Bourcier, Marc, Gratton, David, Kunynetz, Rodion A, Poulin, Yves, Rosoph, Les A, Stingl, Georg, Bauer, Wolfgang M, Salter, Janeen M, Falk, Thomas M, Blödorn-Schlicht, Norbert A, Hueber, Wolfgang, Sommer, Ulrike, Schumacher, Martin M, Peters, Thomas, Kriehuber, Ernst, Lee, David M, Wieczorek, Grazyna A, Kolbinger, Frank, Bleul, Conrad C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676308/
https://ncbi.nlm.nih.gov/pubmed/25828362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.12710
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