Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model

BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive epithelial tumor which shows very poor prognosis and high rate of recurrence, representing an urgent problem for public healthcare. MicroRNAs (miRNAs/miRs) are a class of small, non-coding RNAs that attract great attention because of their...

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Pubblicato in:BMC Bioinformatics
Autori principali: Del Vecchio, Filippo, Gallo, Francesco, Di Marco, Antinisca, Mastroiaco, Valentina, Caianiello, Pasquale, Zazzeroni, Francesca, Alesse, Edoardo, Tessitore, Alessandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676132/
https://ncbi.nlm.nih.gov/pubmed/26652480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0836-1
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