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Neuroendocrine tumors resistant to mammalian target of rapamycin inhibitors: A difficult conversion from biology to the clinic
Deregulation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) - mammalian target of rapamycin (mTOR) signaling pathway is one of the most commonly-involved pathways in tumorigenesis. It has also been reported as altered in neuroendocrine tumors (NETs). mTOR inhibitors used in clinical...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | World J Clin Oncol |
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Prif Awdur: | |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Baishideng Publishing Group Inc
2015
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4675901/ https://ncbi.nlm.nih.gov/pubmed/26677429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v6.i6.194 |
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