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Automated Analysis of Single-Molecule Photobleaching Data by Statistical Modeling of Spot Populations
The number of fluorophores within a molecule complex can be revealed by single-molecule photobleaching imaging. A widely applied strategy to analyze intensity traces over time is the quantification of photobleaching step counts. However, several factors can limit and bias the detection of photobleac...
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Publicado en: | Biophys J |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
The Biophysical Society
2015
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4675885/ https://ncbi.nlm.nih.gov/pubmed/26636946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.035 |
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