The impact of a human IGF-II analog ([Leu(27)]IGF-II) on fetal growth in a mouse model of fetal growth restriction

Enhancing placental insulin-like growth factor (IGF) availability appears to be an attractive strategy for improving outcomes in fetal growth restriction (FGR). Our approach was the novel use of [Leu(27)]IGF-II, a human IGF-II analog that binds the IGF-II clearance receptor IGF-IIR in fetal growth-r...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Charnock, Jayne C., Dilworth, Mark R., Aplin, John D., Sibley, Colin P., Westwood, Melissa, Crocker, Ian P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675800/
https://ncbi.nlm.nih.gov/pubmed/26530156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00379.2015
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