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Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin-4 channelopathies: a decade later

The discovery of AQP4-IgG (a pathogenic antibody that targets the astrocytic water channel aquaporin-4) as the first sensitive and specific biomarker for any inflammatory central nervous system demyelinating disease, has shifted emphasis from the oligodendrocyte and myelin to the astrocyte as a cent...

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Bibliografske podrobnosti
izdano v:Ann N Y Acad Sci
Main Authors: Pittock, Sean J., Lucchinetti, Claudia F.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675706/
https://ncbi.nlm.nih.gov/pubmed/26096370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12794
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