Urinary mitochondrial DNA is a biomarker of mitochondrial disruption and renal dysfunction in acute kidney injury

Recent studies show the importance of mitochondrial dysfunction in the initiation and progression of acute kidney injury (AKI). However, no biomarkers exist linking renal injury to mitochondrial function and integrity. To this end, we evaluated urinary mitochondrial DNA (UmtDNA) as a biomarker of re...

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Pubblicato in:Kidney Int
Autori principali: Whitaker, Ryan M., Stallons, L. Jay, Kneff, Joshua E., Alge, Joseph L., Harmon, Jennifer L., Rahn, Jennifer J., Arthur, John M., Beeson, Craig C., Chan, Sherine L., Schnellmann, Rick G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675682/
https://ncbi.nlm.nih.gov/pubmed/26287315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.240
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