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JEDI T-cells enable targeted cell depletion and investigation of T-cell interactions with virtually any cell population

There are numerous cell types with scarcely understood functions, and whose interactions with the immune system are not well characterized. To facilitate their study, we generated a mouse bearing enhanced green fluorescent protein (EGFP)-specific CD8+ T-cells. Transfer of the T-cells into EGFP repor...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Agudo, Judith, Ruzo, Albert, Park, Eun Sook, Sweeney, Robert, Kana, Veronika, Wu, Meng, Zhao, Yong, Egli, Dieter, Merad, Miriam, Brown, Brian D
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675673/
https://ncbi.nlm.nih.gov/pubmed/26524661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3386
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