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Development and validation of an immunohistochemistry assay to assess glucocorticoid receptor expression for clinical trials of mifepristone in breast cancer

BACKGROUND: Glucocorticoid receptor (GR) activity has been associated with chemotherapy resistance and poor outcomes in patients with triple negative breast cancer (TNBC). The aim of this study was to develop an immunohistochemistry (IHC) assay to assess GR expression in archival formalin-fixed, par...

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Publicado en:Cancer Manag Res
Main Authors: Baker, Gabrielle M, Murphy, Tiffany, Block, Thaddeus, Nguyen, Dat, Lynch, Frank J
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675647/
https://ncbi.nlm.nih.gov/pubmed/26673410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S91546
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