Chronic Treatment with Naltrexone Prevents Memory Retention Deficits in Rats Poisoned with the Sarin Analog Diisopropylfluorophosphate (DFP) and Treated with Atropine and Pralidoxime

Humans and rats poisoned with sarin develop chronic neurological disabilities that are not prevented with standardized antidotal therapy. We hypothesized that rats poisoned with the sarin analogue diisopropylfluorophosphate (DFP) and resuscitated with atropine and pralidoxime would have long-term me...

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Bibliografiske detaljer
Udgivet i:J Med Toxicol
Main Authors: Brewer, Kori L., Tran, Tuan, Meggs, William J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
Fag:
Toxicology Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675601/
https://ncbi.nlm.nih.gov/pubmed/25925946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13181-015-0480-1
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