Gag-Protease Sequence Evolution Following Protease Inhibitor Monotherapy Treatment Failure in HIV-1 Viruses Circulating in East Africa

Around 2.5 million HIV-infected individuals failing first-line therapy qualify for boosted protease inhibitor (bPI)-based second-line therapy globally. Major resistance mutations are rarely present at treatment failure in patients receiving bPI and the determinants of failure in these patients remai...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Principais autores: Sutherland, Katherine A., Goodall, Ruth L., McCormick, Adele, Kapaata, Anne, Lyagoba, Fred, Kaleebu, Pontiano, Thiltgen, Geant, Gilks, Charles F., Spyer, Moira, Kityo, Cissy, Pillay, Deenan, Dunn, David, Gupta, Ravindra K.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
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Sequence Notes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675176/
https://ncbi.nlm.nih.gov/pubmed/26258548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0138
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