Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells

Mechanical ventilation (MV) of patients can cause damage to bronchoalveolar epithelium, leading to a sterile inflammatory response, infection and in severe cases sepsis. Limited knowledge is available on the effects of MV on the innate immune defense system in the human lung. In this study, we demon...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PeerJ
Asıl Yazarlar: Karadottir, Harpa, Kulkarni, Nikhil Nitin, Gudjonsson, Thorarinn, Karason, Sigurbergur, Gudmundsson, Gudmundur Hrafn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: PeerJ Inc. 2015
Konular:
Molecular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675098/
https://ncbi.nlm.nih.gov/pubmed/26664810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1483
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