Učitavanje...

Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells

Mechanical ventilation (MV) of patients can cause damage to bronchoalveolar epithelium, leading to a sterile inflammatory response, infection and in severe cases sepsis. Limited knowledge is available on the effects of MV on the innate immune defense system in the human lung. In this study, we demon...

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Bibliografski detalji
Izdano u:PeerJ
Glavni autori: Karadottir, Harpa, Kulkarni, Nikhil Nitin, Gudjonsson, Thorarinn, Karason, Sigurbergur, Gudmundsson, Gudmundur Hrafn
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675098/
https://ncbi.nlm.nih.gov/pubmed/26664810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1483
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