Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans

INTRODUCTION: A recent study found a significant increase of ABCA7 loss-of-function variants in Alzheimer’s disease (AD) cases compared to controls. Some variants were located on noncoding regions, but it was demonstrated that they affect splicing. Here, we try to replicate the association between A...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Alzheimers Res Ther
Autori principali: Del-Aguila, Jorge L., Fernández, Maria Victoria, Jimenez, Jessica, Black, Kathleen, Ma, Shengmei, Deming, Yuetiva, Carrell, David, Saef, Ben, Howells, Bill, Budde, John, Cruchaga, Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675010/
https://ncbi.nlm.nih.gov/pubmed/26654793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-015-0154-x
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