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Preparation of Effective and Safe Gene Carriers by Grafting Alkyl Chains to Generation 5 Polypropyleneimine

Gene therapy is a novel method to treat a variety of diseases including genetic disorders and cancer. Nonviral gene carriers have now gained considerable attention as gene carrier systems. Polyamidoamine (PAMAM) and polypropyleneimine (PPI) are the two most widely used denderimers in gene delivery s...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Hashemi, Maryam, Parhiz, Hamideh, Mokhtarzadeh, Ahad, Tabatabai, Seyed Meghdad, Farzad, Sara Amel, Shirvan, Haniyeh Rezagholizadeh, Ramezani, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674648/
https://ncbi.nlm.nih.gov/pubmed/25609375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0284-2
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