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Nose-To-Brain Delivery of PLGA-Diazepam Nanoparticles
The objective of the present investigation was to optimize diazepam (Dzp)-loaded poly(lactic-co-glycolic acid) nanoparticles (NP) to achieve delivery in the brain through intranasal administration. Dzp nanoparticles (DNP) were formulated by nanoprecipitation and optimized using Box-Behnken design. T...
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| Publicado no: | AAPS PharmSciTech |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674633/ https://ncbi.nlm.nih.gov/pubmed/25698083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0294-0 |
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