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Tonic nicotinic transmission enhances spinal GABAergic presynaptic release and the frequency of spontaneous network activity

Synaptically driven spontaneous network activity (SNA) is observed in virtually all developing networks. Recurrently connected spinal circuits express SNA, which drives fetal movements during a period of development when GABA is depolarizing and excitatory. Blockade of nicotinic acetylcholine recept...

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Detalhes bibliográficos
Publicado no:Dev Neurobiol
Main Authors: Gonzalez-Islas, Carlos, Garcia-Bereguiain, Miguel Angel, O'Flaherty, Brendan, Wenner, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674379/
https://ncbi.nlm.nih.gov/pubmed/26061781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22315
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