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Silibinin preferentially radiosensitizes prostate cancer by inhibiting DNA repair signaling

Radiotherapy, a frequent mode of cancer treatment, is often restricted by dose-related toxicity and development of therapeutic resistance. To develop a novel and selective radiosensitizer, we studied the radiosensitizing effects and associated mechanisms of silibinin in prostate cancer (PCa). The ra...

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Bibliografske podrobnosti
izdano v:Mol Cancer Ther
Main Authors: Nambiar, Dhanya K., Rajamani, Paulraj, Deep, Gagan, Jain, Anil K., Agarwal, Rajesh, Singh, Rana P.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674330/
https://ncbi.nlm.nih.gov/pubmed/26516160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0348
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