Hedgehog regulates cerebellar progenitor cell and medulloblastoma apoptosis

The external granule layer (EGL) is a proliferative region that produces over 90% of the neurons in the cerebellum but can also malignantly transform into a cerebellar tumor called the medulloblastoma (the most common malignant brain tumor in children). Current dogma considers Hedgehog stimulation a...

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Bibliographic Details
Published in:	Neurobiol Dis
Main Authors:	Noguchi, Kevin Kiyoshi, Cabrera, Omar Hoseá, Swiney, Brant S., Salinas-Contreras, Patricia, Smith, Julie Kathryn, Farber, Nuri B.
Format:	Artigo
Language:	Inglês
Published:	2015
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4674325/ https://ncbi.nlm.nih.gov/pubmed/26319366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.08.020
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Hedgehog regulates cerebellar progenitor cell and medulloblastoma apoptosis

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