A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity

Keratin intermediate filaments (KIFs) protect the epidermis against mechanical force, support strong adhesion, help barrier formation, and regulate growth. The mechanisms by which type I and II keratins contribute to these functions remain incompletely understood. Here, we report that mice lacking a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Kumar, Vinod, Bouameur, Jamal-Eddine, Bär, Janina, Rice, Robert H., Hornig-Do, Hue-Tran, Roop, Dennis R., Schwarz, Nicole, Brodesser, Susanne, Thiering, Sören, Leube, Rudolf E., Wiesner, Rudolf J., Vijayaraj, Preethi, Brazel, Christina B., Heller, Sandra, Binder, Hans, Löffler-Wirth, Henry, Seibel, Peter, Magin, Thomas M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2015
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674273/
https://ncbi.nlm.nih.gov/pubmed/26644517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404147
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