Celiac Disease Histopathology Recapitulates Hedgehog Downregulation, Consistent with Wound Healing Processes Activation

BACKGROUND: In celiac disease (CD), intestinal epithelium damage occurs secondary to an immune insult and is characterized by blunting of the villi and crypt hyperplasia. Similarities between Hedgehog (Hh)/BMP4 downregulation, as reported in a mouse model, and CD histopathology, suggest mechanistic...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Senger, Stefania, Sapone, Anna, Fiorentino, Maria Rosaria, Mazzarella, Giuseppe, Lauwers, Gregory Y., Fasano, Alessio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674131/
https://ncbi.nlm.nih.gov/pubmed/26649570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144634
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