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Uncovering the Molecular Mechanism of Actions between Pharmaceuticals and Proteins on the AD Network

This study begins with constructing the mini metabolic networks (MMNs) of beta amyloid (Aβ) and acetylcholine (ACh) which stimulate the Alzheimer’s Disease (AD). Then we generate the AD network by incorporating MMNs of Aβ and ACh, and other MMNs of stimuli of AD. The panel of proteins contains 49 en...

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Pubblicato in:PLoS One
Autori principali: Cao, Shujuan, Yu, Liang, Mao, Jingyuan, Wang, Quan, Ruan, Jishou
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674063/
https://ncbi.nlm.nih.gov/pubmed/26650760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144387
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