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Investigations on the Oxygen Dependence of a 2-Oxoglutarate Histone Demethylase
Histone N(ε)-methyl lysine demethylases are important in epigenetic regulation. KDM4E is a representative member of the large Fe(II)/2-oxoglutarate dependent family of human histone demethylases. We report kinetic studies on the reaction of KDM4E with O(2): Steady-state assays show KDM4E has a grade...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4673901/ https://ncbi.nlm.nih.gov/pubmed/23092293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121155 |
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