Control of developmentally primed erythroid genes by combinatorial co-repressor actions

How transcription factors (TFs) cooperate within large protein complexes to allow rapid modulation of gene expression during development is still largely unknown. Here we show that the key haematopoietic LIM-domain-binding protein-1 (LDB1) TF complex contains several activator and repressor componen...

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Udgivet i:Nat Commun
Main Authors: Stadhouders, Ralph, Cico, Alba, Stephen, Tharshana, Thongjuea, Supat, Kolovos, Petros, Baymaz, H. Irem, Yu, Xiao, Demmers, Jeroen, Bezstarosti, Karel, Maas, Alex, Barroca, Vilma, Kockx, Christel, Ozgur, Zeliha, van Ijcken, Wilfred, Arcangeli, Marie-Laure, Andrieu-Soler, Charlotte, Lenhard, Boris, Grosveld, Frank, Soler, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673834/
https://ncbi.nlm.nih.gov/pubmed/26593974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9893
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