TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

Despite its importance during viral or bacterial infections, transcriptional regulation of the interferon-β gene (Ifnb1) in activated macrophages is only partially understood. Here we report that TRIM33 deficiency results in high, sustained expression of Ifnb1 at late stages of toll-like receptor-me...

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Pubblicato in:Nat Commun
Autori principali: Ferri, Federica, Parcelier, Aude, Petit, Vanessa, Gallouet, Anne-Sophie, Lewandowski, Daniel, Dalloz, Marion, van den Heuvel, Anita, Kolovos, Petros, Soler, Eric, Squadrito, Mario Leonardo, De Palma, Michele, Davidson, Irwin, Rousselet, Germain, Romeo, Paul-Henri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673826/
https://ncbi.nlm.nih.gov/pubmed/26592194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9900
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