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Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel.

Voltage-gated ion-channel proteins contain "voltage-sensing" domains that drive the conformational transitions between open and closed states in response to changes in transmembrane voltage. We have used site-directed mutagenesis to identify residues affecting the voltage sensitivity of a...

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Autors principals: Thomas, L, Blachly-Dyson, E, Colombini, M, Forte, M
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC46737/
https://ncbi.nlm.nih.gov/pubmed/7685903
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