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Loss of Jagged1 in renin progenitors leads to focal kidney fibrosis
The Notch signaling pathway is required to maintain renin expression within juxtaglomerular (JG) cells. However, the specific ligand which activates Notch signaling in renin-expressing cells remains undefined. In this study, we found that among all Notch ligands, Jagged1 is differentially expressed...
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| Опубликовано в: : | Physiol Rep |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley & Sons, Ltd
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4673620/ https://ncbi.nlm.nih.gov/pubmed/26537340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12544 |
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