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Altered miRNA Signature of Developing Germ-cells in Infertile Patients Relates to the Severity of Spermatogenic Failure and Persists in Spermatozoa

The aim of this study was to assess the cellular miRNA expression behaviour in testes with spermatogenic failure (SpF). We performed a high-throughput screen of 623 mature miRNAs by a quantitative RT-qPCR-based approach in histologically well-defined testicular samples with spermatogenic disruption...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Muñoz, Xavier, Mata, Ana, Bassas, Lluís, Larriba, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673613/
https://ncbi.nlm.nih.gov/pubmed/26648257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17991
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