Blockade of Retinol Metabolism Protects T Cell-Induced Hepatitis by Increasing Migration of Regulatory T Cells

Retinols are metabolized into retinoic acids by alcohol dehydrogenase (ADH) and retinaldehyde dehydrogenase (Raldh). However, their roles have yet to be clarified in hepatitis despite enriched retinols in hepatic stellate cells (HSCs). Therefore, we investigated the effects of retinols on Concanaval...

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Udgivet i:Mol Cells
Main Authors: Lee, Young-Sun, Yi, Hyon-Seung, Suh, Yang-Gun, Byun, Jin-Seok, Eun, Hyuk Soo, Kim, So Yeon, Seo, Wonhyo, Jeong, Jong-Min, Choi, Won-Mook, Kim, Myung-Ho, Kim, Ji Hoon, Park, Keun-Gyu, Jeong, Won-Il
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Molecular and Cellular Biology 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673415/
https://ncbi.nlm.nih.gov/pubmed/26537191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.0218
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